Clonazepam, sold under the brand Klonopin among others, is a medication used to prevent and treat seizures, panic disorder, anxiety, and the movement disorder known as akathisia. It is a tranquilizer of the benzodiazepine class.

Common side effects include sleepiness, poor coordination, and agitation.^[9] Long-term use may result in tolerance, dependence, and withdrawal symptoms if stopped abruptly.^[9] Dependence occurs in one-third of people who take clonazepam for longer than four weeks.^[8] There is an increased risk of suicide, particularly in people who are already depressed.^[9][10] If used during pregnancy it may result in harm to the fetus.^[9] Clonazepam binds to GABA_A receptors, thus increasing the effect of the chief inhibitory neurotransmitter γ-aminobutyric acid (GABA).^[8]